Cleaning and decontamination formula for surfaces contaminated with prion-infected material
AssigneeSTERIS Inc.
InventorsGerald E. McDonnell, Herbert J. Kaiser, Kathleen M. Antloga, Mildred R. Bernardo
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Abstract
A method of treating the surfaces of medical instruments which are contaminated with prions includes contacting the surface with a composition containing a source of peroxide ions, such as hydrogen peroxide, at a molar concentration of at least 1.5M peroxide (equivalent to approximately 5% hydrogen peroxide) and preferably, about 2M peroxide (approximately 7% hydrogen peroxide). The composition is optionally in the form of a gel. The composition is retained in contact with the surfaces for about 1–2 hours until all or substantially all prion contamination is removed.
Claims17
A method of treatment of a prion-contaminated surface of a medical device which has been used in a surgical procedure, comprising:
- contacting the surface which is contaminated with prions with an aqueous gel composition for sufficient time to at least substantially reduce the prions on the surface, the composition comprising:
- at least 5% by weight of hydrogen peroxide;
- 5–30% by weight of a humectant;
- at least 0.1% by weight of a corrosion inhibitor;
- and
- a hydrogen peroxide stabilizer.
A method of treatment of a prion-contaminated surface, comprising:
- contacting the surface which is contaminated with prions with an aqueous gel composition for at least one hour to at least substantially reduce the prions on the surface the composition comprising:
- at least 5% by weight of hydrogen peroxide;
- and
- a humectant for retaining moisture on the surface the humectant including sorbitol.
A method for treatment of a device contaminated with prions, comprising:
- coating surfaces of the prion-contaminated device with a gel composition which includes peroxide at a molar concentration of at least 1.5 M and at least 5% of a humectant;
- and
- retaining the gel in contact with the surfaces for at least one hour to substantially reduce prions on the device.
Dependencies are inferred from the claim text.