Elongase genes and uses thereof
AssigneeAbbott Laboratories
InventorsPradip Mukerji, Tapas Das, Yung-Sheng Huang, Jennifer Parker-Barnes, Amanda E. Leonard, Jennifer M. Thurmond
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AssigneeAbbott Laboratories
InventorsPradip Mukerji, Tapas Das, Yung-Sheng Huang, Jennifer Parker-Barnes, Amanda E. Leonard, Jennifer M. Thurmond
Estimating the term…
The subject invention relates to the identification of four genes involved in the elongation of polyunsaturated acids (i.e., “elongases”) and to uses thereof. Two of these genes are also involved in the elongation of monounsaturated fatty acids. In particular, elongase is utilized in the conversion of gamma linolenic acid (GLA) to dihomogamma linolenic acid (DGLA) and in the conversion of DGLA or 20:4n-3 to eicosapentaenoic acid (EPA). DGLA may be utilized in the production of polyunsaturated fatty acids, such as arachidonic acid (AA), docosahexaenoic acid (DHA), EPA, adrenic acid, ω6-docosapentaenoic acid or ω3-docosapentaenoic acid which may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
An isolated nucleic acid molecule having a nucleotide sequence with at least 95% homology to SEQ ID NO:
A method of producing an elongase enzyme comprising the steps of:
A vector comprising:
Dependencies are inferred from the claim text.