Therapeutical combination against cancer
AssigneeLaboratoire Goemar SA
InventorsJean-Claude Yvin, Edouard Panak, Vaclav Vetvicka
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Abstract
The present invention relates to compositions and methods for treating humans and warm-blood animals suffering from cancer. More particularly, a therapeutical treatment in which a monoclonal antibody is administered with either β-(1,3)-glucan like laminarin or a oligo-β-(1,3)-glucan and a pharmaceutically acceptable carrier, to patients suffering from cancer are described.
Claims9
A therapeutical method comprising administration of a composition comprising a monoclonal antibody with an oligo-β-(1,3)-glucan and a pharmaceutically acceptable carrier, to a human being or to a warm blooded animal suffering from breast cancer in an amount which is effective to treat the breast cancer, wherein the monoclonal antibody is any monoclonal antibody specific to molecular determinants present on breast cancer cells and simultaneously able to activate complement.
A pharmaceutical composition under the form of an injection, ointment, pulmonary spray comprising a therapeutically effective amount of a monoclonal antibody and an oligo-β-(1,3)-glucan or formula (1)
- in which n=1 to 10,
- or a salt pharmaceutically acceptable salt thereof,
- and a pharmaceutical acceptable carrier,
- said composition being free of any other glucan.
A pharmaceutical composition under the form of an injection, ointment, pulmonary spray comprising a therapeutically effective amount of a monoclonal antibody and an oligo-β-(1,3)-glucan or formula (1)
- in which n=2 or n=3,
- or a salt pharmaceutically acceptable salt thereof,
- and a pharmaceutical acceptable carrier,
- said composition being free of any other glucan.
Dependencies are inferred from the claim text.