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US 7,070,762 B2Granted
Delivery of analgesics through an inhalation route
AssigneeAlexza Pharmaceuticals, Inc.
InventorsJoshua D. Rabinowitz, Alejandro C. Zaffaroni
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AssigneeAlexza Pharmaceuticals, Inc.
InventorsJoshua D. Rabinowitz, Alejandro C. Zaffaroni
Estimating the term…
The present invention relates to the delivery of analgesics through an inhalation route. Specifically, it relates to aerosols containing acetaminophen, orphenadrine or tramadol that are used in inhalation therapy. In a method aspect of the present invention, an analgesic is administered to a patient through an inhalation route. The method comprises: a) heating a composition, wherein the composition acetaminophen, orphenadrine or tramadol, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles with less than 5% acetaminophen, orphenadrine or tramadol degradation products. In a kit aspect of the present invention, a kit for delivering acetaminophen, orphenadrine or tramadol through an inhalation is provided which comprises: a) a thin coating of an acetaminophen, orphenadrine or tramadol composition and b) a device for dispensing said thin coating as a condensation aerosol.
A method of treating pain in a patient comprising administering a therapeutic amount of a drug condensation aerosol to the patient by inhalation,
A method of administering a drug condensation aerosol to a patient comprising administering the drug condensation aerosol to the patient by inhalation,
A kit for delivering a drug condensation aerosol comprising:
Dependencies are inferred from the claim text.