Treatment device for topical photodynamic therapy and method of using same
AssigneeAdvanced Photodynamic Technologies, Inc.
InventorMerrill A. Biel
Life of this patent
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Abstract
The invention relates to a light emitting treatment device including one or more light members which are configured to emit energy for photodynamic therapy at a treatment field. The treatment device may be made of a polymeric material configured to conform to a body surface. The light members may be disposed in a substantially uniform array and be configured to emit energy in a substantially uniform pattern. The light emitting treatment device may provide light variable feedback to a control apparatus. The light emitting treatment device may further include a heat dissipating layer, a layer of gold or gold alloy, or a layer of adhesive disposed on at least one of the one or more surfaces. Methods of using the treatment device are also disclosed.
Claims16
A method of performing a photodynamic therapy at a treatment field, said method comprising the steps of:
- providing a photosensitive material to the treatment field;
- providing a flexible polymer patch element having a treatment surface and an opposite surface displaced a patch thickness away from the treatment surface, said patch element having a light block layer on the treatment surface and a light reflective layer on the opposite surface;
- emitting light from a plurality of light emitting members disposed within the patch element between the light blocking layer and the light reflective layer with at least a portion of the patch element being between the plurality of light emitting members and the light block layer and at least another portion of the patch element being between the plurality of light emitting members and the light reflective layer;
- applying the patch element at the treatment field, said treatment surface conforming to a surface of a tissue field;
- directly passing at least some of the emitted light to the treatment field through a thickness of the flexible polymer patch which is substantially less than a local thickness of the patch element;
- reflecting at least some of the emitted light off the light reflective layer and back towards the treatment surface, said reflected light passing through an effective thickness of the flexible polymer patch which is substantially greater than the local thickness of the patch element and as a result said reflected light being more diffused relative to the light passing directly to the treatment surface;
- and
- blocking at least some of the emitted light with the light blocking layer, together the passed light and the reflected light providing a light dosage rate to the treatment field of between 0 mw/cm2 to about 150 mw/cm2.
A method for photodynamic treatment at a treatment site, said method comprising the steps of:
- providing a photosensitive material to a treatment field;
- positioning a patch element upon a surface of the treatment field, said patch element having a body and being of a flexible polymer so as to conform to the surface of the treatment field, said patch element having a treatment surface in contact with the treatment field and an opposite surface, said patch element having a light reflective layer proximate the opposite surface and a light blocking layer proximate to the treatment field;
- illuminating a light member within the body of the patch element;
- passing some of light from the light member directly to the treatment field;
- reflecting some of the light from the light member off the reflective layer and back to the treatment field;
- and
- blocking some of the light from the light member from passing directly into the treatment field, wherein the light member provides a light dosage rate to the treatment field of between 0 mw/cm2 to 150 mw/cm2.
Dependencies are inferred from the claim text.