Methods for raising pre-adult anadromous fish
AssigneeMariCal, Inc.
InventorsH. William Harris, Jr., David R. Russell, Jacqueline Nearing, Marlies Betka
Life of this patent
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Abstract
Methods, compositions and kits for improving the raising of pre-adult anadromous fish, or preparing pre-adult anadromous fish for transfer to seawater. The methods involve adding at least one Polyvalent Cation Sensing Receptor (PVCR) modulator to the freshwater in an amount sufficient to increase expression and/or sensitivity of at least one PVCR; and adding feed for fish consumption to the freshwater, wherein the feed comprises an amount of NaCl sufficient to contribute to a significantly increased level of the PVCR modulator in serum of the pre-adult anadromous fish.
Claims25
A method of growing pre-adult anadromous fish in freshwater having at least one Polyvalent Cation Sensing Receptor (PVCR) modulator in the freshwater in an amount sufficient to modulate at least one of the expression and the sensitivity of at least one PVCR, the method comprising:
- adding feed for fish consumption to the freshwater, wherein the feed contains an amount of NaCl sufficient to contribute to a significantly increased level of said at least one PVCR modulator in serum of the pre-adult anadromous fish.
A method of growing pre-adult anadromous fish in freshwater having between about 0.3 mM and about 10.0 mM of calcium and between about 0.5 mM and 10.0 mM of magnesium, the method comprising:
- adding feed for fish consumption to the freshwater, wherein the feed contains an amount of NaCl sufficient to contribute to a significantly increased level of said calcium and magnesium in serum of the pre-adult anadromous fish.
A method of improving the raising of pre-adult anadromous fish, wherein the pre-adult anadromous fish are maintained in freshwater prior to transfer to seawater, comprising:
- a) determining the level of at least one PVCR modulator in freshwater;
- b) based on step a), adding at least one PVCR modulator to the freshwater in an amount sufficient to modulate at least one of the expression and the sensitivity of at least one PVCR;
- b) adding feed for fish consumption to the freshwater, wherein the feed contains an amount of NaCl sufficient to contribute to a significantly increased level of said at least one PVCR modulator in serum of the pre-adult anadromous fish.
A method of growing pre-adult anadromous fish in freshwater having at least one PVCR modulator in the freshwater in an amount sufficient to modulate at least one of the expression and the sensitivity of at least one PVCR, the method comprising:
- adding feed for fish consumption to the freshwater, wherein the feed contains an amount of an agent sufficient to contribute to a significantly increased level of said at least one PVCR modulator in serum of the pre-adult anadromous fish.
A method of growing pre-adult anadromous fish in freshwater having between about 0.3 mM and about 10.0 mM of calcium and between about 0.5 mM and 10.0 mM of magnesium, the method comprises:
- adding feed for fish consumption to the freshwater, wherein the feed contains an amount of an agent sufficient to contribute to a significantly increased level of said calcium and magnesium in serum of the pre-adult anadromous fish.
A method of improving the raising of pre-adult anadromous fish, wherein the pre-adult anadromous fish are maintained in freshwater prior to transfer to seawater, comprising:
- a) determining the level of at least one PVCR modulator in freshwater;
- b) based on step a), adding at least one PVCR modulator to the freshwater in an amount sufficient to modulate at least one of the expression and the sensitivity of at least one PVCR;
- b) adding feed for fish consumption to the freshwater, wherein the feed contains an amount of an agent sufficient to contribute to a significantly increased level of said at least one PVCR modulator in serum of the pre-adult anadromous fish.
A method of improving the raising of pre-adult anadromous fish, wherein the pre-adult anadromous fish are maintained in freshwater prior to transfer to seawater, comprising:
- a) adding to the freshwater at least one compound selected from the group consisting of:
- a divalent cation, a trivalent cation, an aminoglycoside, a organic polycation, an amino acid, a Type I Calcimimetic, a Type II Calcimimetic, 1,25 dihydroxyvitamin D, a cytokine, and macrophage chemotatic peptide;
- and
- b) adding feed for fish consumption to the freshwater, wherein the feed contains an amount of NaCl sufficient to contribute to a significantly increased level of said compound in serum of the pre-adult anadromous fish.
A method of improving the raising of pre-adult anadromous fish, wherein the pre-adult anadromous fish are maintained in freshwater prior to transfer to seawater, comprising:
- a) adding to the freshwater at least one selected from the group consisting of:
- a divalent cation, a trivalent cation, an aminoglycoside, a organic polycation, an amino acid, a Type I Calcimimetic, a Type II Calcimimetic, 1,25 dihydroxyvitamin D, a cytokine, and macrophage chemotatic peptide;
- and
- b) adding feed for fish consumption to the freshwater, wherein the feed contains an amount of an agent sufficient to contribute to a significantly increased level of said compound in serum of the pre-adult anadromous fish.
Dependencies are inferred from the claim text.