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US 7,067,697 B2Granted
Cationic liposomes for gene transfer
AssigneeVanderbilt University
InventorXiang Gao
Life of this patent
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Abstract
The present invention relates to synthetic cationic lipids, liposome formulations and the use of such compounds to introduce functional bioactive agents into cultured cells.
Claims10
A method for introducing a biologically active agent into a cell of a plant or animal comprising:
- contacting said cell with lipid vesicles comprising a lipid having the formula:
- or a pharmaceutically acceptable salt or ester thereof, wherein R1 and R2 are the same and are from C6 to C24 alkyl or C6 to C24 alkenyl and containing said biologically active agent, whereby said biologically active agent is taken up into said cell.
A method for introducing a biologically active agent into a cell of a plant or animal comprising:
- contacting said cell with a biologically active agent in the presence of lipid vesicles comprising a lipid having the formula:
- or a pharmaceutically acceptable salt or ester thereof, wherein R1 and R2 are the same and are from C6 to C24 alkyl or C6 to C24 alkenyl, whereby said biologically active agent is taken up into said cell.
Dependencies are inferred from the claim text.