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US 7,067,694 B2Granted
Halogen-substituted amino dicarboxylic acid derivatives as medicaments for treating cardiovascular diseases
AssigneeBayer Aktiengesellschaft
InventorsMichael Härter, Michael G. Hahn, Claudia Hirth-Dietrich, Andreas Knorr, Elke Stahl, Johannes-Peter Stasch, Frank Wunder
Life of this patent
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Abstract
Compounds of the general formula (I) wherein R1 represents halogen, R2 and R3 represent H or halogen, and R4 represents C3-8-cycloalkyl or optionally substituted phenyl, pharamceutical compositions containing such materials, and methods of using such materials in the treatment of various diseases are disclosed and claimed.
Claims9
A compound of the general formula (I)
- wherein
- R1 is located in the meta- or para-position to the ethylamino radical and represents halogen;
- R2 represents H or halogen;
- R3 represents H or halogen;
- R4 represents C3-8-cycloalkyl or phenyl, where the phenyl radical may additionally carry a substituent from the group consisting of halogen, CN, OMe, CF3;
- with the proviso that R4 does not represent phenyl which carries a substituent CF3 or OMe in the para-position to the point of attachment if, simultaneously, R1 is in the meta-position to the ethylamino radical and represents F and R2 and R3 each represent H;
- or a pharmaceutically acceptable salt or stereoisomer thereof.
4 more elements
Dependencies are inferred from the claim text.