Promoters exhibiting endothelial cell specificity and methods of using same
AssigneeVascular Biogenics Ltd.
InventorDror Harats
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Abstract
An isolated polynucleotide functional as a promoter in eukaryotic cells is disclosed. The isolated polynucleotide includes an endothelial specific enhancer element as detailed herein. Further disclosed is a method of expressing a nucleic acid sequence of interest in endothelial cells.
Claims19
An isolated polynucleotide functional as a promoter in eukaryotic cells, the isolated polynucleotide comprising an enhancer element including at least one copy of the sequence set forth in SEQ ID NO:8.
An isolated polynucleotide functional as a promoter in eukaryotic cells, the isolated polynucleotide comprising an enhancer element including the sequence set forth in SEQ ID NO:
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Dependencies are inferred from the claim text.