Nucleotide and deduced amino acid sequences of tumor gene Int6
AssigneeThe United States of America, as represented by the Secretary, Department of Health and Human Services
InventorsAntonio Marchetti, Fiamma Buttitta, Gilbert H. Smith, Robert Callahan
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Abstract
The present invention discloses the isolation of the human and murine wild-type Int6 gene and the cDNAs sorresponding to these genes. The invention further describes the use of reagents derived from the nucleic acid and amino acid sequences of the Int6 gene in diagnostic methods, immunotherapy, gene therapy and as vaccines.
Claims12
A purified antibody or fragment thereof that specifically binds SEQ ID NO:
- 4, or a fragment of about 20 to about 24 consecutive amino acids of SEQ ID NO:
- 4.
An isolated antibody that specifically binds amino acids 262–281 or amino acids 57–71 of SEQ ID NO:
- 4.
Dependencies are inferred from the claim text.