Control of arthropods in animals
AssigneeRhone-Poulenc Agro
InventorsScot Kevin Huber, Yves Ribeill, Susan Marie McComb, Michael James Malaska, David Teh-Wei Chou, Adalberto Perez de Leon
Life of this patent
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Abstract
A method of controlling parasites in or on an animal comprising orally administering to the animal a parasiticidally effective, substantially non-emetic 1-arylpyrazole.
Claims41
A method of controlling parasites in or on an animal in need of such control, said method comprising orally administering to said animal a parasiticidally effective, substantially non-emetic amount of a 1-arylpyrazole having the formula (XX):
- wherein:
- R201 is cyano, C(O)alkyl, C(S)NH2, alkyl, C(═NOH)NH2 or C(═NNH2)NH2;
- R202 is S(O)hR203;
- R203 is alkyl or haloalkyl;
- R204 is —N(R205)C(O)aryl wherein aryl is thienyl or furyl, each of which is unsubstituted or is substituted by alkoxy, haloalkyl or haloaen;
- R205 is alkyl, haloalkyl, cycloalkyl, halocycloalkyl, cycloalkylalkyl, halocycloalkylalkyl, alkoxyalkyl, haloalkoxyalkyl, C3-C5 alkenyl, C3-C5 haloalkenyl, C3-C5 alkynyl, or C3-C5 haloalkynyl;
- X1 is C—R212;
- R211 and R212 are, independently, halogen, hydrogen, CN or NO2;
- R213 is halogen, haloalkyl, haloalkoxy, —S(O)kCF3, or —SF5;
- and
- h and k are, independently, 0, 1, or 2;
- or a veterinarily acceptable salt thereof.
A compound having the formula (XX):
- wherein:
- R201 is cyano, C(O)alkyl, C(S)NH2, alkyl, C(═NOH)NH2 or C(═NNH2)NH2;
- R202 is S(O)hR203;
- R203 is alkyl or haloalkyl;
- R204 is —N(R205)C(O)aryl wherein aryl is thienyl or furyl, each of which is unsubstituted or is substituted by alkoxy, haloalkyl or halogen;
- R205 is alkyl, haloalkyl, cycloalkyl, halocycloalkyl, cycloalkylalkyl, halocycloalkylalkyl, alkoxyalkyl, haloalkoxyalkyl, C3-C5 alkenyl, C3-C5 haloalkenyl, C3-C5 alkynyl, or C3-C5 haloalkynyl;
- X1 C—R212;
- R211 and R212 are, independently, halogen, hydrogen, CN or NO2;
- R213 is halogen, haloalkyl, haloalkoxy, —S(O)kCF3, or —SF5;
- and
- h and k are, independently, 0, 1 or 2;
- or a veterinarily acceptable salt thereof.
A composition comprising a parasiticidally effective, substantially non-emetic amount of a compound having the formula (XX):
- wherein:
- R201 is cyano, C(O)alkyl, C(S)NH2, alkyl, C(═NOH)NH2 or C(═NNH2)NH2;
- R202 is S(O)hR203;
- R203 is alkyl or haloalkyl;
- R204 is —N(R205)C(O)aryl wherein aryl is thienyl or furyl, each of which is unsubstituted or is substituted by alkoxy, haloalkyl or halogen;
- R205 is alkyl, haloalkyl, cycloalkyl, halocycloalkyl, cycloalkylalkyl, halocycloalkylalkyl, alkoxyalkyl, haloalkoxyalkyl, C3-C5 alkenyl, C3-C5 haloalkenyl, C3-C5 alkynyl, or C3-C5 haloalkynyl;
- X1 is C—R212;
- R211 and R212 are, independently, halogen, hydrogen, CN or NO2;
- R213 is halogen, haloalkyl, haloalkoxy, —S(O)kCF3, or —SF5;
- and
- h and k are, independently, 0, 1, or 2;
- or a veterinarily acceptable salt thereof;
- and a veterinarily acceptable carrier therefor.
A compound having the formula (XX):
- wherein:
- R201 is cyano;
- R202 is S(O)hR203;
- R203 is alkyl or haloalkyl;
- R204 is —N(R205)C(O)aryl wherein aryl is thienyl or furyl each of which is unsubstituted or substituted by alkoxy, haloalkyl or halogen;
- R205 is alkyl, haloalkyl, cycloalkyl, halocycloalkyl, cycloalkylalkyl, halocycloalkylalkyl, alkoxyalkyl, haloalkoxyalkyl, C3-C5 alkenyl, C3-C5 haloalkenyl, C3-C5 alkynyl, or C3-C5 haloalkynyl;
- X1 is C—R212;
- R211 and R212 are, independently, halogen, hydrogen, CN or NO2;
- R213 is halogen, haloalkyl, haloalkoxy, —S(O)kCF3, or —SF5;
- and
- h and k are, independently, 0, 1 or 2;
- or a veterinarily acceptable salt thereof.
Dependencies are inferred from the claim text.