Compositions with enhanced antimicrobial efficacy against E. coli
AssigneeBausch & Lomb Incorporated
InventorsErning Xia, Joseph C. Salamone, Roya Borazjani, Alyce K. Dobie, Deborah McGrath, Zhenze Hu, Daniel M. Ammon, Jr.
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Abstract
Ophthalmic compositions include a polycation material to enhance antimicrobial efficacy against bacteria such as E. coli. The compositions include eye drop and contact lens treating solutions. A preferred polycation material is cationic cellulose derivatives.
Claims12
A method for enhancing antimicrobial efficacy of a composition against E. coli comprising including a polyquaternium-10 cationic cellulosic polymer in said composition containing a primary antimicrobial agent.
An ophthalmic composition comprising a primary antimicrobial agent, and a polyquaternium-10 cationic cellulosic polymer in an aqueous solution, wherein said cationic cellulosic polymer enhances the antimicrobial efficacy of the primary antimicrobial agent.
An ophthalmic composition comprising a primary antimicrobial agent and a polyquaternium-10 cationic cellulosic polymer that enhances the antimicrobial efficacy of said primary antimicrobial agent, wherein said composition adequately preserves said composition against E. coli, whereas a similar composition lacking the polyquaternium-10 cationic cellulosic polymer does not adequately preserve said similar composition against E. coli.
Dependencies are inferred from the claim text.