Monoclonal antibody, its immunoreactive fragment and hybridoma
AssigneeKaneka Corporation
InventorsTakaaki Ohara, Kenji Yamashita, Tetsu Kakutani, Seishi Kyoizumi
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Abstract
It is an object to utilize a novel HSCA-3 antigen occurring in immature hemopoietic stem cells and a monoclonal antibody recognizing said antigen in 1) the immunoassay or flow cytometry involving antibody labeling and 2) the isolation and purification of immature hemopoietic stem cells from human bone marrow cells, umbilical code blood or blood enriched in human hemopoietic stem cells by mobilization with G-CSF. It is directed to a novel HSCA-3 antigen occurring in immature hemopoietic stem cells and to a monoclonal antibody or an immunoreactive fragment thereof which recognizes said antigen.
Claims10
A monoclonal antibody which recognizes human immature hemopoietic stem cells but does not recognize CD34+ Jurkat cells, and
- which binds to the same antigen as does the monoclonal antibody produced by a hybridoma having an accession number of FERM BP-8045.
A hybridoma which has an accession number of FERM BP-8045.
Dependencies are inferred from the claim text.