Methods and means for modulating PGE synthase activity
AssigneeKarolinska Innovations AB
InventorsPer-Johan Jakobsson, Bengt Samuelsson, Ralf Morgenstern, Anthony Ford-Hutchinson, Joseph Mancini
Life of this patent
Estimating the term…
Abstract
Isolated PGE synthase, provided from encoding nucleic acid. Methods of production and use. Assays for modulators, especially inhibitors, of PGE synthase activity.
Claims5
An isolated and pure polypeptide which is a PGE synthase and which comprises the amino acid sequence of SEQ ID NO. 2.
An isolated and pure polypeptide which is a PGE synthase and which consists of an active portion of SEQ ID NO:2 wherein said active portion comprises amino acids 30-152 of SEQ ID NO. 2.
An isolated and pure polypeptide which is a PGE synthase and which consists of an active portion of SEQ ID NO:2 wherein said active portion comprises amino acids 1-130 of SEQ ID NO. 2.
An isolated and pure polypeptide which is a PGE synthase and which consists of an active portion of SEQ ID NO:2 wherein said active portion comprises amino acids 30-130 of SEQ ID NO. 2.
Dependencies are inferred from the claim text.