Cell line for the expression of an α2δ2 calcium channel subunit and methods of use
AssigneeWarner-Lambert Company
InventorTi-Zhi Su
Life of this patent
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Abstract
Described is a method for determining the binding ability of a compound to bind to an α2δ2 subunit of a calcium channel comprising: providing an α2δ2 subunit of a calcium channel, contacting the subunit with the compound, and determining the binding ability of the compound to bind to the subunit.
Claims12
A method for determining the binding ability of a compound to a cell expressing an α2δ2 subunit of a calcium channel comprising providing a cell line expressing an α2δ2 sub-unit of a calcium channel, said cell line having ATCC No. PTA-1823;
- contacting the cells with the compound;
- and determining the binding ability of the compound to the cells.
A cell line having ATCC No. PTA-1823.
A method for determining the binding ability of a compound to an α2δ2 subunit of a calcium channel comprising;
- providing an α2δ2 subunit of a calcium channel encoded by the nucleotide sequence set forth in accession NO. AF 042792;
- contacting the α2δ2 subunit with the compound;
- and determining the binding ability of the compound to the α2δ2 subunit.
Dependencies are inferred from the claim text.