Pharmaceutical compositions containing Vitamin D and calcium, their preparation and therapeutic use
AssigneeMenarini International Operations Luxembourg S.A.
InventorsMaurizio Valleri, Alessandro Tosetti
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Abstract
Described herein is a pharmaceutical composition containing Vitamin D and calcium, comprising a binding agent chosen from among the group consisting of: propylene glycol, a polyethylene glycol presenting a molecular weight comprised between 300 and 1500, liquid paraffin or silicone oil, useful for the treatment of nutritional deficiency of calcium and Vitamin D in the elderly.
Claims12
A granular pharmaceutical composition which consists essentially of Vitamin D and calcium phosphate, as active principles and a binding agent selected from the group consisting of propylene glycol, a polyethylene glycol of molecular weight between 300 and 400;
- liquid paraffin and silicone oil, said Vitamin D being present in an amount of 500–1000 I.U. of Vitamin D and said calcium salt being present in a ratio of 1–2 g of calcium, calculated as elemental calcium, for each 500–1000 I.U. of Vitamin D.
A pharmaceutical composition in a tablet dosage form which consists essentially of:
- Tribasic calcium phosphate
- 3.100 g
- (corresponding to 1200 mg of Ca++)
- Cholecalciferol (Vit. D3) 100,000 IU/g
- 0.008 g
- (corresponding to 800 IU)
- Liquid paraffin
- 0.500 g
- Sodium carboxymethyl cellulose
- 0.050 g
- Sodium saccharin
- 0.015 g
- Orange flavoring
- 0.100 g
- Sorbitol q.s. to
- 4.400 g.
A pharmaceutical composition in a tablet dosage form which consists essentially of:
- Tribasic calcium phosphate
- 3.100 g
- (corresponding to 1200 mg of Ca++)
- Cholecalciferol (Vit. D3) 100,000 IU/g
- 0.008 g
- (corresponding to 800 IU)
- Silicone oil
- 0.500 g
- Sodium carboxymethyl cellulose
- 0.050 g
- Sodium saccharin
- 0.015 g
- Orange flavoring
- 0.100 g
- Sorbitol q.s. to
- 4.400 g.
Dependencies are inferred from the claim text.