Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer
AssigneeAgensys, Inc.
InventorsPia M. Challita-Eid, Arthur B. Raitano, Mary Faris, Rene S. Hubert, Karen Jane Meyrick Morrison, Aya Jakobovits
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Abstract
A gene (designated 161P2F10B) and its encoded protein are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in the cancers listed in Table I. Consequently, 161P2F10B provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 161P2F10B gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit a humoral or cellular immune response.
Claims12
A method of inhibiting growth of a tumor cell that expresses SEQ ID NO:743 or SEQ ID NO:745 comprising:
- contacting said cell with an antibody or fragment thereof specifically binds to a protein having an amino acid sequence of SEQ ID NOS:
- 743 or 745, wherein the antibody or fragment thereof binds to and inhibits the growth of the tumor cell via the protein.
Dependencies are inferred from the claim text.