Modified live Edwardsiella tarda vaccine for aquatic animals
AssigneeThe United States of America as represented by the Secretary of Agriculture
InventorsJoyce J. Evans, Phillip H. Klesius, Craig A. Shoemaker
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Abstract
A safe and effective live vaccine against Edwardsiella tarda in fish was created through the induction of rifampicin resistance in a native Edwardsiella tarda isolate. Single immersion exposure or injection of fish stimulated acquired immunity against virulent E. tarda infection.
Claims9
A rifampicin resistant mutant strain of Edwardsiella tarda deposit accession no. NRRL B-30305.
The rifampicin resistant mutant strain of Edwardsiella tarda which is substantially biologically pure.
A vaccine composition comprising an immunologically effective amount of a rifampicin resistant mutant strain of Edwardsiella tarda deposit accession no. NRRL B-30305.
Dependencies are inferred from the claim text.