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US 7,064,208 B2Granted
Substantially pure cilostazol and processes for making same
AssigneeTeva Pharmaceutical Industries Ltd.
InventorsMarioara Mendelovici, Nina Finkelstein, Gideon Pilarski
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Abstract
The present invention provides substantially pure cilostazol. The present invention also provides cilostazol particles that have reduced particle size.
Claims9
A process for preparing cilostazol comprising:
- a) combining 6-hydroxy-3,4-dihydroquinolinone and at least one alkali metal hydroxide;
- b) removing water using molecular sieves;
- c) adding 1-cyclohexyl-5-(4-halobutyl)-tetrazole;
- and
- d) recovering cilostazol.
2 more elements
Dependencies are inferred from the claim text.