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US 7,064,188 B2Granted
Monoclonal antibodies which identify the glycoprotein carrying the CA125 epitope
AssigneeBoard of Trustees of the University of Arkansas
InventorTimothy J. O'Brien
Life of this patent
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Abstract
Hybridomally produced monoclonal antibodies specifically immunoreactive with the glycoprotein carrying the CA 125 epitope. Monoclonal antibodies recognize both high and low molecular weight subunits of the antigen, and identify the antigen in the cytoplasm and the extracellular matrix of CA 125 producing cells. An immunoassay for the detection of CA 125 utilizing the monoclonal antibodies is described.
Claims7
A monoclonal antibody wherein said antibody is identified as M 11.
A hybridoma cell line capable of producing antibody M 11.
Dependencies are inferred from the claim text.