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US 7,064,182 B2Granted
Human serpin
AssigneeZymoGenetics, Inc.
InventorJames L. Holloway
Life of this patent
Estimating the term…
Abstract
Members of the serine protease family play a role in carefully controlled processes, such as blood coagulation, fibrinolysis, complement activation, fertilization, and hormone production. The enzymatic activity of the serine proteases is regulated in part by serpins, serine protease inhibitors. Serpin dysfunction is associated with various disorders, including emphysema, blood clotting disorders, cirrhosis, Alzheimer disease, and Parkinson disease. Zserp11 is a new member of the serine protease inhibitor family.
Claims6
An isolated polypeptide, comprising an amino acid sequence selected from the group consisting of:
- the amino acid sequence of SEQ ID NO:2, amino acid residues 46 to 137 of SEQ ID NO:2, amino acid residues 154 to 285 of SEQ ID NO:2, and amino acid residues 296 to 364 of SEQ ID NO:2.
Dependencies are inferred from the claim text.