Peg-based macromonomers, chemically inert polymers prepared therefrom and the use of these polymers for organic synthesis and enzyme reactions
AssigneeCarlsberg A/S
InventorsMorten Meldal, Jens Buchardt, Joerg Rademann
Life of this patent
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Abstract
The present invention relates to macromonomers containing ethylene glycol repeat units, to chemically inert polymers prepared therefrom and to the use of such polymers in solid phase biochemical assays. A macromonomer of polyethylene glycol having repeat units in the range 6–300 and having at least one end terminated by an ether group having formula (I) where m is an integer of 0–10, a is an integer of 1–4, and R is H or alkyl or aryl or arylalkyl; or having formula (II) where m is an integer of 1–10, and R is H or alkyl or aryl or arylalkyl
Claims17
A macromonomer having the structure:
- where ñ is a real number of 6–300,
- and where X and Y each independently is a group of the formula
- where m is an integer of 1–10, and R is H or alkyl or aryl or arylalkyl,
- or where X is —OH, and Y is a group of the formula
- where m is an integer of 1–10, and R is H or alkyl or aryl or arylalkyl.
A macromonomer having the structure:
- where R is H or alkyl or aryl or arylalkyl,
- and ñ is a real number of 6–300 as defined above
- and where X, Y and Z each independently is OH or a group of the formula
- where m is an integer of 1–10, a is as defined above, and R is H or alkyl or aryl or arylalkyl;
- provided that at least one of X, Y or Z is a group of the formula
- where m is an integer of 1–10, a is as defined above, and R is H or alkyl or aryl or arylalkyl.
Dependencies are inferred from the claim text.