Quinoline derivatives process of synthesis and medicaments containing these derivatives

A 2-carbamoyl-8-hydroxyquinoline-7-carboxylic acid compound or its pharmaceutically acceptable salt, wherein said compound corresponds to formula I:

• in which
• X represents an alkyl-(CH2)n— chain in which n is equal to 0, 1 or 2, O, or N,
• Z represents an aromatic ring which may contain heteroatoms chosen from O, N or S, as substitutions for the carbon atoms constituting said aromatic ring, it being possible or otherwise for this ring to be substituted with Rb,
• Rb represents 1 to 3 identical or different substituents chosen from the group —OH, —OR, —COOH, —COOR, —COH, —COR, —NH2, —NH(R), —NH(R, R′), —SH, —SR and CN,
• Ra represents a hydrogen atom or a group —(CH2)n′—Y, for which n′ is equal to 0, 1, 2 or 3 and Y represents CR3, —COOR, —COOR, —CN, —OH, —OR, SR, or an aryl group optionally substituted with Rb,
• R and R′, which are identical or different, represent a linear or branched alkyl chain of 1 to 4 carbon atoms.