Gene and use thereof
AssigneeTakeda Chemical Industries, Ltd.
InventorsHideaki Tojo, Nozomi Katayama, Shigeya Kakimoto
Life of this patent
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Abstract
A protein and DNA encoding the same are useful as preventives/remedies for diseases such as hypoglycemia, etc. The protein of the present invention is also useful as a reagent for screening a compound that inhibits the binding of the protein of the present invention to IRAP (insulin responsive aminopeptidase) or to GLUT4 (glucose transporter 4). The compound that inhibits the binding of the protein of the present invention to IRAP or GLUT4 is useful as a preventive/remedy for diseases, e.g., hyperglycemia, diabetes mellitus, etc.
Claims5
An isolated protein containing the amino acid sequence represented by SEQ ID NO:
- 1 and having an activity of binding to IRAP or GLUT4, or a salt thereof.
An isolated protein containing the amino acid sequence represented by SEQ ID NO:
- 15, or a salt thereof.
Dependencies are inferred from the claim text.