Uses of antibodies against AChE and peptides thereof
AssigneeYissum Research Development Company of the Hebrew University of Jerusalem
InventorsHermona Soreq, Daniela Kaufer, Alon Friedman, Shlomo Seidman
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Abstract
The invention relates to antibodies recognizing acetylcholinesterase or a C-terminal peptide derived from acetyl-cholinesterase, useful in diagnosing central nervous system (CNS) stress, elevated glucocorticoid level, disruption of the blood-brain barrier or Alzheimer's disease. The invention also relates to methods for the diagnosis of central nervous system (CNS) stress, elevated glucocorticoid level or disruption of the blood-brain barrier in a mammal, by use of the antibodies of the invention.
Claims3
An antibody recognizing a C-terminal peptide derived from acetylcholinesterase said C-terminal peptide comprising the I4 peptide and denoted by SEQ ID No:1, for diagnosing central nervous system (CNS) stress.
Dependencies are inferred from the claim text.