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US 7,062,385 B2Granted
Intelligent electro-optical nucleic acid-based sensor array and method for detecting volatile compounds in ambient air
AssigneeTufts University
InventorsJoel E. White, John S. Kauer
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Abstract
The present invention generally relates to nucleic acid-based sensors and methods for detecting volatile analytes. More particularly, this invention relates to nucleic acid-based optical sensors, sensor arrays, sensing systems and sensing methods for intelligent sensing and detection of unknown materials by way of real-time feedback and control of sampling conditions.
Claims8
A method for detecting a volatile compound in an air sample comprising the steps of:
- a) contacting said air sample with a nucleic acid/fluorophore-based sensor array comprising:
- i) a substrate;
- and
- ii) a nucleic acid attached to a fluorophore dispersed on said substrate,
- wherein said nucleic acid is dried onto the substrate, and wherein said nucleic acid is attached to a fluorophore providing a characteristic optical response when subjected to excitation light energy in the presence of a volatile compound in the air sample;
- and
- b) detecting the presence or absence of said volatile compound in the air sample.
4 more elements
Dependencies are inferred from the claim text.