US 7,060,721 B1 · Imidazole compounds and medicinal use thereof

Abstract

Imidazole compounds represented by general formula (I): wherein each symbol is as defined in the specification, and salts thereof, and a pharmaceutical composition containing same are provided. These compounds are useful in treating the diseases curable based on a hypoglycemic action, and the diseases curable based on a cGMP-PDE inhibitory action, a smooth muscle relaxing action, a bronchodilating action, a vasodilating action, a smooth muscle cell inhibitory action and an allergy inhibitory action.

Claims6

Dependent claims

An imidazole compound of the formula:

wherein
R2 is a lower alkyl;
R3 is chlorine;
R4 is (1) a lower alkenyl optionally substituted by aryl or heterocyclic group, (2) aryl optionally substituted by lower alkenyl, (3) lower alkyl, or (4) heterocyclic group optionally substituted by halogen;
R6 is lower alkenyl optionally substituted by phenyl, or lower alkynyl optionally substituted by phenyl;
and
L is ethylene,
where aryl is defined as unsubstituted aryl or alkyl-substituted aryl, or a salt thereof.

5 more elements

Dependencies are inferred from the claim text.

Facts

Application

09/869,135Filed 20 Dec 1999

Priority

JP 10-36736224 Dec 1998

Granted

13 Jun 2006

Term ends

Not estimatedThe source records don’t support an estimate.

Classification10 codes

C07D 233/64
Having two double bonds between ring members or between ring members and non-ring members: with substituted hydrocarbon radicals attached to ring…
A61P 3/10
For glucose homeostasis: for hyperglycaemia, e.g. antidiabetics
A61P 43/00
Drugs for specific purposes, not provided for in groups a61p1/00-a61p41/00
C07D 233/90
With hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals,…:…

Imidazole compounds and medicinal use thereof

Life of this patent

Imidazole compounds and medicinal use thereof

Life of this patent

Abstract

Claims6