US 7,060,059 B2 · System and method for initiating and maintaining continuous, long-term control of a concentration of a substance in a patient using a feedback or model-based controller coupled to a single-needle or multi-needle intradermal (ID) delivery device

Abstract

A closed loop therapy system for controlling a concentration of a substance, such as blood glucose concentration, in the body of a user. The system and method employ a sensor system that measures a glucose level in the body, a controller that uses the measured glucose levels to generate an output that can be used to automatically or manually control an intradermal insulin infusion system to set a constant or time-varying profile of target blood glucose concentrations in a user, and then infuse an appropriate amount of insulin into the body of the user so as to reach and maintain the target values of the blood glucose concentration.

Claims51

Dependent claims

A system for controlling the concentration of a substance in a patient, the system comprising:

a delivery device comprising at least one needle configured with a length sufficient to deliver a material to the intradermal compartment of said patient to result in at least one of rapid uptake of said material and rapid clearance of said material;
and
a controller, adapted to determine the concentration of said substance in the patient that occurs in response to said material delivered to the patient, and to provide an output that is adaptable for use to control the delivery device to control an amount of said material delivered to the patient based on the concentration of said substance.

Dependencies are inferred from the claim text.

Facts

Application

10/683,466Filed 14 Oct 2003 · us provisional application

Priority

11 Oct 2002

Published

US 2004/0152622 A15 Aug 2004

Granted

13 Jun 2006

Term ends

Not estimatedThe source records don’t support an estimate.

Classification12 codes

A61K 38/28
Hormones: insulins
A61M 31/002
Devices for introducing or retaining media, e.g. remedies, in cavities of the body: devices for releasing a drug at a continuous and controlled…
A61P 3/10
For glucose homeostasis: for hyperglycaemia, e.g. antidiabetics
G16H 20/17
Relating to drugs or medications, e.g. for ensuring correct administration to patients: delivered via infusion or injection

System and method for initiating and maintaining continuous, long-term control of a concentration of a substance in a patient using a feedback or model-based controller coupled to a single-needle or multi-needle intradermal (ID) delivery device

Life of this patent

System and method for initiating and maintaining continuous, long-term control of a concentration of a substance in a patient using a feedback or model-based controller coupled to a single-needle or multi-needle intradermal (ID) delivery device

Life of this patent

Abstract

Claims51