Method for prevention and/or treatment of infections and inflammatory conditions using a combination of lactic acid bacteria
AssigneeVSL Pharmaceuticals, Inc.
InventorClaudio De Simone
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Abstract
The disclosure is of a combination of lactic acid bacteria comprising: (a) a first component consisting of at least one strain of H2O2-producing lactic acid bacteria; and (b) a second component consisting of at least one strain of arginine-utilizing lactic acid bacteria. The disclosure is also of the use of this combination for making a food supplement, a hygiene product or a pharmaceutical preparation for the prevention and/or treatment of infections and inflammatory conditions caused by bacteria, viruses or fungi, especially in the mouth, vagina, urethra, nose, eyes and ears.
Claims16
A method of inhibiting the growth of pathogenic bacteria, virus or fungi in a body cavity or orifice of a subject suffering from infectious or inflammatory conditions, comprising administering to a subject in need thereof an effective amount of a combination of lactic acid bacteria comprising a first component (a) consisting of at least one strain of H2O2-producing lactic acid bacteria, and a second component (b) consisting of at least one strain of arginine-utilizing lactic acid bacterial wherein component (a) is selected from the group consisting of the strains of the species Lactobacillus crispatus, Lactobacillus salivarius and Lactobacillus casei, and component (b) is selected from the group consisting of the strains of the species Lactobacillus brevis DSM 11988, a non-H2O2-producing Lactobacillus gasseri and Lactobacillus fermentum, provided that when component (a) is Lactobacillus casei, component (b) is not Lactobacillus gasseri or Lactobacillus fermentum, and when component (a) is Lactobacillus crispatus, component (b) is not Lactobacillus fermentum.
The method according to claim 10, wherein component (a) is Lactobacillus crispatus and component (b) is Lactobacillus fermentum.
A method of inhibiting the growth of pathogenic bacteria, virus or fungi in a body cavity or orifice of a subject suffering from infectious or inflammatory conditions comprising administering to a subject in need thereof an effective amount of a combination of lactic acid bacteria comprising a first component (a) consisting of at least one strain of H2O2-producing lactic acid bacteria, and a second component (b) consisting of at least one strain of arginine-utilizing lactic acid bacterial wherein component (a) is selected from the group consisting of the strains of the species Lactobacillus crispatus, Lactobacillus salivarius and Lactobacillus casei, and component (b) is Lactobacillus brevis DSM 11988.
Dependencies are inferred from the claim text.