Systems and methods for detecting symptoms of hypoglycemia

A system for detecting symptoms of hypoglycemia in a diabetic individual, comprising:

• a temperature sensing system for producing a temperature signal representative of a skin temperature of the diabetic individual;
• a conductance sensing system for producing a conductance signal representative of a level of perspiration of the diabetic individual;
• a signal estimation system responsive to the temperature signal and to the conductance signal for producing a basal conductance reference representative of a basal level of perspiration;
• a threshold system responsive to the basal conductance reference and to the skin temperature signal for producing a conductance threshold representative of a hypoglycemic level of perspiration;
• and
• an alarm system responsive to the conductance signal and to the conductance threshold for producing an indication of the presence of hypoglycemic symptoms.

A system for detecting symptoms of hypoglycemia in a diabetic individual, comprising:

• a temperature sensing system for producing a temperature signal representative of a skin temperature of the diabetic individual;
• a conductance sensing system for producing a conductance signal representative of a level of perspiration of the diabetic individual;
• a trending system responsive to the temperature signal for producing a slope estimate representative of a rate of change of the skin temperature over a predetermined interval;
• a temperature threshold system responsive to the conductance signal and to the temperature signal for producing a slope threshold representative of a hypoglycemic decline in skin temperature observed over the predetermined interval;
• a temperature alarm system responsive to the slope estimate and to the slope threshold for producing an indication of the presence of hypoglycemic symptoms;
• a signal estimation system responsive to the temperature signal and to the conductance signal for producing a basal conductance reference representative of a basal level of perspiration;
• a conductance threshold system responsive to the basal conductance reference and to the temperature signal for producing a conductance threshold representative of a hypoglycemic level of perspiration;
• a conductance alarm system responsive to the conductance signal and to the conductance threshold for producing an indication of the presence of hypoglycemic symptoms;
• and
• a selector system for selecting an operating mode from a plurality of operating modes.

A method of detecting symptoms of hypoglycemia in a diabetic individual, comprising:

• producing a temperature signal representative of a skin temperature of the diabetic individual;
• producing a conductance signal representative of a level of perspiration of the diabetic individual;
• producing a slope estimate representative of a rate of change of the skin temperature over a predetermined interval in response to the temperature signal;
• producing a slope threshold representative of a hypoglycemic decline in skin temperature observed over the predetermined interval in response to the conductance signal and the temperature signal;
• and
• producing an indication of the presence of hypoglycemic symptoms in response to the slope estimate and the slope threshold.

A method of detecting symptoms of hypoglycemia in a diabetic individual, comprising:

• producing a temperature signal representative of a skin temperature of the diabetic individual;
• producing a conductance signal representative of a level of perspiration of the diabetic individual;
• producing a basal conductance reference representative of a basal level of perspiration in response to the temperature signal and the conductance signal;
• producing a conductance threshold representative of a hypoglycemic level of perspiration in response to the basal conductance reference and the skin temperature signal;
• and
• producing an indication of the presence of hypoglycemic symptoms in response to the conductance signal and the conductance threshold.

A method of detecting symptoms of hypoglycemia in a diabetic individual, comprising:

• producing a temperature signal representative of a skin temperature of the diabetic individual;
• producing a conductance signal representative of a level of perspiration of the diabetic individual;
• producing a slope estimate representative of a rate of change of the skin temperature over a predetermined interval in response to the temperature signal;
• producing a slope threshold representative of a hypoglycemic decline in skin temperature observed over the predetermined interval in response to the conductance signal and the temperature signal;
• producing an indication of the presence of hypoglycemic symptoms in response to the slope estimate and the slope threshold;
• producing a basal conductance reference representative of a basal level of perspiration in response to the temperature signal and the conductance signal;
• producing a conductance threshold representative of a hypoglycemic level of perspiration in response to the basal conductance reference and the temperature signal;
• producing an indication of the presence of hypoglycemic symptoms in response to the conductance signal and the conductance threshold;
• and
• selecting an operating mode from a plurality of operating modes.