A method for serially operating a charged particle beam apparatus having a charged particle source for producing a primary beam of charged particles, a condenser lens for shaping the primary beam of charged particles, a beam shaping means adapted to switch between a collimation of the primary beam to a width appropriate for serial imaging as well as a collimation of the primary beam to a width appropriate for parallel imaging, a scanning means for deflecting said primary beam of charged particles, and a sectorized detector for detecting secondary charged particles, the method comprising:
- providing the charged particle beam apparatus;
- adjusting the beam shaping means for collimating the primary beam of charged particles to collimate said primary beam of charged particles to the width appropriate for serial imaging of a sample,
- scanning said sample using the scanning means, wherein said primary beam of charged particles is directed to a respective position of a single pixel on said sample, and
- detecting secondary charged particles by means of the sectorized detector, wherein signals produced by individual sectors of said detector are merged to form a signal corresponding to said single pixel.