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AssigneeThe Regents of the University of California
InventorsSylvaine Cases, Scot J. Stone, Ping Zhou, Robert V. Farese, Jr., Chi-Liang Eric Yen
Estimating the term…
Nucleic acid compositions encoding polypeptide products with diglyceride acyltransferase and/or monoacylglycerol acyltransferase activity, as well as the polypeptide products encoded thereby, i.e., mammalian DGAT2α and MGAT1 polypeptide products, and methods for producing the same, are provided. Also provided are: methods and compositions for modulating DGAT2α and MGAT1 activity; DGAT2α and MGAT1 transgenic cells, animals and plants, as well as methods for their preparation; and methods for making diglyceride, diglyceride compositions, triglycerides and triglyceride compositions, as well as the compositions produced by these methods. The subject methods and compositions find use in a variety of different applications, including research, medicine, agriculture and industry applications.
A polynucleotide present in other than its natural environment encoding a polypeptide that exhibits monoacylglycerol and/or diacylglycerol acyltransferase activity and comprising a nucleotide sequence that has at least 95% nucleotide sequence identity to the sequence set forth in SEQ ID NO:03.
Dependencies are inferred from the claim text.