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US 7,030,289 B2Granted
Stabilization of milk from transgenic animals
AssigneePPL Therapeutics (Scotland) Limited
InventorsIan Robert Cottingham, Graham Edward McCreath
Life of this patent
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Abstract
The present invention relates to the stabilization of milk from transgenic animals. In particular, the invention relates to the protection of proteins (e.g. fibrinogen) expressed in milk from transgenic animals by co-expression of a serine proteinase inhibitor (e.g., α1-antitrypsin) in the milk of the transgenic animals.
Claims2
A method for stabilizing heterologous fibrinogen expressed in the milk of a transgenic non-human mammal comprising co-expressing, with said heterologous fibrinogen in the milk of said mammal, alpha-1-antitrypsin operably linked to a milk-protein specific promoter.
Dependencies are inferred from the claim text.