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US 7,030,251 B2Granted
Modifications of the trometamol salt of R-thioctic acid as well as a process for their production
AssigneeViatris GmbH & Co. KG
InventorsGunter Laban, Wolfgang Sauer, Annegret Jannasch
Life of this patent
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Abstract
The invention relates to new modifications of the trometamol salt of R-thioctic acid of the formula I, processes for their production, pharmaceutical preparations containing these modifications, and their medical application.
Claims2
Modification A of the compound I
- characterised by the X-ray diffraction pattern in which reflections not coinciding with the reflections of the other modifications are observed inter alia at 14.87°2θ20(5.96 Å), 19.99°2θ(4.44 Å), 20.88°2θ(4.25 Å), 22.78°2θ(3.90 Å), 24.53°2θ(3.63 Å), 25.66°2θ(3.47 Å), 30.05°2θ(2.97 Å) and at 37.29°2θ(2.41 Å).
Modification B of the compound I characterised by the X-ray diffraction pattern in which reflections not coinciding with the reflections of the other modification are observed inter alia at 13.80°2θ(6.41 Å), 15.22°2θ(5.82 Å), 17.50°2θ6(5.06 Å) and at 23.48°2θ(3.79 Å).
Dependencies are inferred from the claim text.