Piperidinylamino-thieno[2,3-d] pyrimidine compounds

A compound having the formula

• wherein
• R1 and R2 are independently be hydrogen;
• lower alkyl, C1–C6 cycloalkyl or cycloheteroalkyl;
• halogens or halo-substituted alkyl;
• or R1 and R2, taken together, form a C5–C7 cycloalkyl or cycloheteroalkyl ring;
• R3 and R4 are independently Ar which is a single or conjugated substituted or unsubstituted aromatic ring structure;
• R5 is H, (C1–C5)alkyl, (C1–C6)cycloalkyl, halogen substituted alkyl, NH2, NHMe, NMe2, NHEt, NH(Et)2, NH(Pr), N(Pr)2;
• and
• n is 0, 1, 2, 3, 4 or 5;
• and pharmaceutically acceptable salts and/or esters thereof.