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US 7,030,228 B1Granted
Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
AssigneeMiltenyi Biotec GmbH
InventorsJuergen Schmitz, Andrzej Dzionek, David William Buck
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Abstract
The invention provides antigen-binding fragments specific for dendritic cells and effective in treatment and/or diagnosing a variety of disorders. Methods of use are also provided as are methods for screening for additional such antigen-binding fragments and the products obtained thereby.
Claims16
An isolated antigen-binding fragment comprising a polypeptide domain that specifically binds a BDCA-2 protein encoded by SEQ ID NO:1;
- wherein said BDCA-2 protein is encoded by exons 1–6;
- exons 1 and 3–6;
- exons 1–2 and 4–6;
- or exons 1–3 and 5–6 of SEQ ID NO:1.
1 more element
Dependencies are inferred from the claim text.