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US 7,030,214 B2Granted
Ureins derived from α, ω, diamino acids and process for their preparation
AssigneeSolvay (Societe Anonyme)
InventorsRoland Callens, Georges Blondeel, Marc Anteunis, Frank Becu
Life of this patent
Estimating the term…
Abstract
Ureins are obtained by reaction, in basic medium, between an Nω-(aryloxycarbonyl)diamino acid and a compound containing a free amino group. The chirality of the compounds is outstandingly well preserved.
Claims15
Nω-Carboxyalkylcarbamoyl-α,ω-diamino acids of general formula
- in which A represents a bivalent group consisting of a linear carbon chain formed from 4 to 8 carbon atoms, which chain is optionally substituted by one or a number of groups chosen from C1–C3 alkyl groups and functional groups comprising at least one oxygen or sulphur atom and in which R3-NαH represents an α-amino acid or a peptide comprising the α-amino acid and the Nα is a nitrogen atom attached to the α-carbon of the α-amino acid.
A peptide of general formula
- in which A is a bivalent group consisting of a linear carbon chain formed from 2 carbon atoms, which chain is substituted by at least one substituent selected from the group consisting of a functional group comprising at least one sulphur atom and a functional group comprising at least one oxygen atom selected from carboxyl, acyl, hydroxyl and alkoxy group.
Dependencies are inferred from the claim text.