Crystalline polymorph of venlafaxine hydrochloride and methods for the preparation thereof
AssigneeWyeth
InventorsKadum Abdul Nabi Ali, Jun Han, Yong Jai Lee
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Abstract
This invention relates to a highly thermally stable novel anhydrous crystalline polymorphic form of venlafaxine hydrochloride, methods for the preparation thereof, and its use.
Claims10
Venlafaxine hydrochloride having an X-ray powder diffraction pattern substantially the same as that shown in FIG. 1.
Substantially pure venlafaxine hydrochloride having an X-ray powder diffraction pattern substantially the same as that shown in FIG. 1.
A crystalline polymorph of venlafaxine hydrochloride exhibiting an X-ray powder diffraction pattern having characteristic peaks expressed in degrees 2θ at about 5.67, 7.28, 9.14, 9.67, 10.77, 11.31, 14.01, 14.54, 14.85, 15.48, 15.81, 16.17, 16.94, 17.68, 18.02, 18.48, 19.29, 19.69, 20.46, 20.74, 21.86, 22.33, 22.67, 22.95, 23.17, 24.06, 24.61, 25.13, 26.62, 26.97, 27.64, 28.25, 29.01, 29.96, 31.01, 31.61, 32.75, 34.54, 35.50, 35.95 and 36.91.
A crystalline polymorph of venlafaxine hydrochloride exhibiting an X-ray powder diffraction pattern having characteristic peaks expressed in degrees 2θ at about 5.67, 7.28, 9.14, 9.67, 10.77, 14.01, 14.54, 16.17, 19.69, and 20.74.
Dependencies are inferred from the claim text.