Methods for the treatment of neuroleptic and related disorders using ziprasidone metabolites
AssigneeSepracor Inc.
InventorsTimothy J. Barberich, Paul D. Rubin, William E. Yelle
Life of this patent
Estimating the term…
Abstract
The invention relates to novel methods using, and pharmaceutical compositions comprising, ziprasidone metabolites. The methods and compositions of the invention are suitable for the treatment of neuroleptic and related disorders. The invention further encompasses methods of preparing ziprasidone sulfoxide and ziprasidone sulfone.
Claims19
A method of treating or prophylaxis of a disorder ameliorated by the inhibition of serotonin reuptake at 5-HT2 receptors and/or the inhibition of dopamine reuptake at dopamine D2 receptors in a patient which comprises administering to a patient in need of such treatment or prophylaxis a therapeutically effective amount of a ziprasidone metabolite, or a pharmaceutically acceptable salt, solvate, hydrate, or clathrate thereof.
A method of treating or prophylaxis of a neuroleptic disorder in a patient which comprises administering to a patient in need of such treatment or prophylaxis a therapeutically effective amount of a ziprasidone metabolite, or a pharmaceutically acceptable salt, solvate, hydrate, or clathrate thereof.
A method of treating or prophylaxis of a neuroleptic disorder in a patient which comprises administering to a patient in need of such treatment or prophylaxis a therapeutically effective amount of ziprasidone sulfoxide, or a pharmaceutically acceptable salt, solvate, hydrate, or clathrate thereof.
A method of treating or prophylaxis of a neuroleptic disorder in a patient which comprises administering to a patient in need of such treatment or prophylaxis a therapeutically effective amount of ziprasidone sulfone, or a pharmaceutically acceptable salt, solvate, hydrate, or clathrate thereof.
Dependencies are inferred from the claim text.