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US 7,030,127 B2Granted
Composition and medical devices utilizing bioabsorbable polymeric waxes
AssigneeEthicon, Inc.
InventorsAruna Nathan, Joel Rosenblatt, Steven C. Arnold
Life of this patent
Estimating the term…
Abstract
The present invention is directed to medical devices, pharmaceutical or agricultural compositions, and seeds, each containing a synthetic, bioabsorbable, biocompatible polymeric wax that is the reaction product of a polybasic acid or derivative thereof, a polyol and a fatty acid, the polymeric wax having a melting point less than about 70° C., as determined by differential scanning calorimetry.
Claims12
A composition, comprising:
- a therapeutically effective amount of a therapeutic agent, and a polymeric wax comprising the reaction product of a polybasic acid or derivative thereof and a monoglyceride, said monoglyceride selected from the group consisting of monostearoyl glycerol, monopalmitoyl glycerol, monomyrisitoyl glycerol, monocaproyl glycerol, monodecanoyl, monolauroyl glycerol, monolinoleoyl glycerol and monooleoyl glycerol, said polymeric wax comprising an aliphatic polyester backbone having monoglyceride groups pending therefrom and having a melting point less than about 70° C., as determined by differential scanning calorimetry.
A composition, comprising:
- a therapeutically effective amount of a therapeutic agent, and a polymeric wax copolymer comprising the reaction product of a fatty acid, a polyol, and at least two polybasic acids or derivatives thereof selected from the group consisting of succinic acid, succinic anhydride, malic acid, tartaric acid, citric acid, diglycolic acid and diglycolic anhydride, said polymeric wax copolymer comprising an aliphatic polyester backbone having fatty acid ester groups pending therefrom and having a melting point less than about 70° C., as determined by differential scanning calorimetry.
A composition, comprising:
- a therapeutically effective amount of risperidone, and a polymeric wax comprising the reaction product of a polybasic acid or derivative thereof, a fatty acid and a polyol, said polymeric wax comprising an aliphatic polyester backbone having fatty acid ester groups pending therefrom and having a melting point less than about 70° C., as determined by differential scanning calorimetry.
A composition, comprising:
- a therapeutically effective amount of a therapeutic agent, and a polymeric wax comprising the reaction product of a polybasic acid or derivative thereof, a fatty acid and a polyol, said polymeric wax comprising an aliphatic polyester backbone having fatty acid ester groups pending therefrom andilaving a melting point between about 25° C. and about 70° C., as determined by differential scanning calorimetry.
Dependencies are inferred from the claim text.