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US 7,030,121 B2Granted
Pyrazolopyrazine compound and pharmaceutical use thereof
AssigneeAstellas Pharma Inc.
InventorsAtsushi Akahane, Akira Tanaka
Life of this patent
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Abstract
A pyrazolopyrazine compound of the following formula (I). wherein R1 is hydrogen or a suitable substituent; and R2 is hydrogen or halogen, or a salt thereof. The pyrazolopyrazine compound (I) and salt thereof of the present invention are adenosine antagonists and are useful for the prevention and/or treatment of depression, dementia (e.g. Alzheimer's disease, cerebrovascular dementia, dementia accompanying Parkinson's disease, etc.), Parkinson's disease, anxiety, pain, cerebrovascular disease (e.g. stroke, etc.), heart failure and the like.
Claims6
A pyrazolopyrazine compound of the following formula (I):
- wherein
- R1 is hydrogen, lower alkyl, ar(lower)alkyl or cyclo(lower)alkyl which may be interrupted by an oxygen atom;
- R2 is hydrogen or halogen,
- or a salt thereof.
1 more element
Dependencies are inferred from the claim text.