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US 7,030,081 B2Granted
Muteins of the CGRP 1-7 peptide fragment and use thereof as nicotinic neuronal receptor enhancers
AssigneeS.I.S.S.A.- Scuola Internazionale Superiore di Studi Avanzati
InventorsAndrea Nistri, Silvia Di Angelantonio
Life of this patent
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Abstract
Muteins of the Ser-Cys-Asn-Thr-Ala-Thr-Cys sequence from the N-terminal 1-7 fragment of the CGRP peptide, possessing an enhancing action on the activation of neuronal nicotinic receptors, their pharmaceutical compositions containing the same and their use for the potential therapy of neurological diseases are described.
Claims3
An isolated peptide consisting of the amino acid residues 1–4 of SEQ ID No. 1 or the amino acid residues 1–5 of SEQ ID No. 1 or the amino acid residues 1–6 of SEQ ID No. 1 or the amino acid of SEQ ID No. 2.
Dependencies are inferred from the claim text.