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US 7,029,755 B2Granted
Silane copolymer compositions containing active agents
AssigneeC. R. Bard, Inc.
InventorsRichard N. Terry, Kevin Walsh
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AssigneeC. R. Bard, Inc.
InventorsRichard N. Terry, Kevin Walsh
Estimating the term…
The invention is drawn to silane copolymers prepared from the reaction of one or more polyisocyanates with one or more lubricious polymers having at least two functional groups, which may be the same or different, that are reactive with an isocyanate functional group and with one or more organo-functional silanes having at least two functional groups, which may be the same or different, that are reactive with an isocyanate functional group and at least one functional group reactive with a silicone rubber substrate. The silane copolymers of the invention can be used as coatings that are elastic when dry, lubricious when wet, and resist wet abrasion. These copolymers are useful as coatings for polysiloxane (rubber) and other difficult to coat substrates, especially for medical devices, such as catheters. These silane copolymers can contain active agents such as antimicrobials, pharmaceuticals, herbicides, insecticides, algaecides, antifoulants, and antifogging agents.
A composition comprising a silane copolymer and from 0.1% to 50% of an active agent on the dry weight of the composition, wherein said silane copolymer comprising one or more polyisocyanates, one or more organo-functional silanes, and one or more polyols.
An article of manufacture comprising a substrate and a coating wherein the coating comprises a silane copolymer and from 0.1% to 50% of an active agent based on the dry weight of the composition, wherein said silane copolymer comprises one or more polyisocyanates, one or more organo-functional silanes, and one or more polyols.
A method for the manufacture of a coated article comprising dipping, spraying, or brushing a composition comprising a silane copolymer and at least one active agent onto the surface of the article and allowing the composition to dry, wherein said active ingredient is present in an amount from 0.1% to 50% based on the dry weight of the composition, and wherein said silane copolymer comprising one or more polyisocyanates, one or more organo-functional silanes, and one or more polyols.
A composition comprising a polyurethane-urea-silane copolymer and from 0.1% to 50% of an active ingredient based on the dry weight of the composition.
A composition comprising:
An article of manufacture comprising a substrate and a coating wherein the coating comprises a polyurethane-urea-silane copolymer and from 0.1% to 50% of an active agent based on the dry weight of the composition.
An article of manufacture comprising a substrate and a coating wherein the coating comprises:
Dependencies are inferred from the claim text.