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US 7,029,701 B2Granted
Composition for the treatment and prevention of ischemic events
AssigneeAndrx Pharmaceuticals, Inc.
InventorChih-Ming Chen
Life of this patent
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AssigneeAndrx Pharmaceuticals, Inc.
InventorChih-Ming Chen
Estimating the term…
The invention relates to pharmaceutical compositions comprising omeprazole and aspirin wherein the combination is useful for the treatment and prevention of cardiovascular events including heart attacks and platelet aggregation leading to a potential cardiac event. A variety of drug delivery systems may be utilized to deliver the combination of active ingredients. The preferred delivery system utilizes a tablet or capsule containing an inert sugar core particle that is coated with subparticles of a coated omeprazole wherein the coating contains omeprazole, a binder, a surface active agent and a basifying agent along with a filler. The aspirin may be combined with this formulation to coat the sugar sphere or it may be part of a separate coating composition that forms a multilayer system that is ultimately coated with an enteric coating and then formed into the tablet or capsule by conventional means.
A sustained release formulation comprising:
A stable pharmaceutical composition of omeprazole and aspirin for oral administration comprising:
A controlled release formulation comprising:
A controlled release formulation comprising:
A stable pharmaceutical composition of omeprazole and aspirin for oral administration comprising:
Dependencies are inferred from the claim text.