Tubular construct for implantation
AssigneeGeorgia Tech Research Corporation
InventorsJoseph D. Berglund, Robert M. Nerem, Athanassios Sambanis
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Abstract
The present invention is directed to devices for repair, replacement or augmentation of soft tissues in an organism. The devices comprise cellular compositions comprising cells and preferably, structural proteins such as collagen or elastin. The devices can also be used in methods for testing the effects of agents on soft tissues.
Claims15
A tubular construct suitable for implantation, comprising, a biological support structure comprising a gel matrix admixed with a cellular composition comprising one or more types of cells and products of cells, and an intact elastin scaffold.
A method of repair of soft tissue, comprising, implanting a tubular construct suitable for implantation, comprising, a biological support structure comprising a gel matrix admixed with a cellular composition comprising one or more types of cells and products of cells, and an intact elastin scaffold.
A method for determining activity of agents, comprising, a) providing a tubular construct, comprising, a biological support structure comprising a gel metrix admixed with a cellular composition comprising one or more types of cells and products of cells, and an intact elastin scaffold, b) adding at least one agent to the tubular construct and c) determining an effect on the tubular construct.
Dependencies are inferred from the claim text.