Hepsin antagonist and methods of use
OwnerShu-Wha Lin, I-Shing Yu +3inventors
InventorsShu-Wha Lin, I-Shing Yu, Teng-Nan Lin, Pao-Hsien Chu, Hosheng Tu
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Abstract
A method for treating or preventing infarction of a patient comprising administering a hepsin antagonist with a dosage effective to suppress or inactivate hepsin's expression over a sustained period.
Claims8
A method for treating infarction of a patient comprising administering hepsin blocking peptides with a dosage effective amount of said hepsin blocking peptides to inactivate hepsin activity within 12 hours of post-infarction, wherein said blocking peptides consist of human hepsin amino acids sequence no. 241–260.
A method for treating infarction of a patient comprising administering a dose of hepsin antagonist to an infarcted region or an infarct-risk region with a dosage effective amount to inactivate hepsin activity at about the infarcted or infarct-risk region within 12 hours of post-infarction, wherein said hepsin antagonist is a hepsin blocking peptides consisting of human hepsin amino acids sequence no. 241–260.
Dependencies are inferred from the claim text.