Nasal spray steroid formulation and method
AssigneeBalance Pharmaceuticals, Inc.
InventorsMalcolm C. Pike, Darcy V. Spicer, AnnaMarie Daniels, John R. Daniels
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Abstract
The present invention relates to an improvement in a method of contraception, in treatment of benign gynecological disorders, and in hormone replacement. The improved method includes administering intranasally an estrogenic compound and an androgenic compound, and in some embodiments an optional progestin compound, in a once-daily bolus formulation comprised of the two or three steroids complexed with a cyclodextrin. An intranasal delivery system for administration of the formulation is also described.
Claims10
A method for contraception, for treatment of benign gynecological disorders, or for hormone replacement, comprising,
- administering intranasally a bolus of a formulation comprised of an estrogenic compound and an androgenic compound complexed with a cyclodextrin;
- whereby said intranasal administering of said bolus is effective to achieve a physiologic effect comparable to that produced when the estrogenic compound and the androgenic compound are administered transdermally.
Dependencies are inferred from the claim text.