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US 7,025,869 B2Granted
Nitric oxide delivery system
AssigneeCyTerra Corporation
InventorsDavid H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
Life of this patent
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Abstract
Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.
Claims17
A method of delivering nitric oxide to a mammal comprising:
- disposing a cathode and an anode in a solution of a nitric oxide precursor that includes a precursor salt;
- applying a voltage across the cathode and anode to generate nitric oxide substantially devoid of nitrogen dioxide;
- contacting a transport gas with the solution of nitric oxide precursor to form a therapeutic gas;
- and
- transporting the therapeutic gas to a mammal.
2 more elements
Dependencies are inferred from the claim text.