Piperidine derivatives and process for their production
AssigneeAMR Technology, Inc.
InventorThomas E. D'Ambra
Life of this patent
Estimating the term…
Abstract
The present invention relates to substantially pure piperidine derivative compounds of the formulae: wherein R1 is hydrogen or hydroxy; R2 is hydrogen; or R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; R3 is —COOH or —COOR4; R4 has 1 to 6 carbon atoms; A, B, and D are the substituents of their respective rings, each of which may be different or the same and are hydrogen, halogens, alkyl, hydroxy, alkoxy, or other substituents. A process of preparing such piperidine derivative compounds in substantially pure form is also disclosed.
Claims3
A compound of the formula:
- wherein
- A is one or more substituents, each of which may be different or the same, and are selected from the group consisting of hydrogen, halogens, alkyl, hydroxy or alkoxy;
- R5 is —N(R6)2;
- and
- R6 is an alkyl with 1 to 6 carbons.
A process of preparing a mixture of regioisomers of the formula:
- wherein
- A is one or more substituents, each of which may be different or the same, and are selected from the group consisting of hydrogen, halogens, alkyl, hydroxy or alkoxy;
- R5 is —N(R6)2;
- and
- R6 is an alkyl with 1 to 6 carbons;
- said process comprising:
- acylating a starting compound of the formula:
- with a compound of the formula:
- wherein
- X is a halogen.
Dependencies are inferred from the claim text.