Isotopically labelled DNA
AssigneeThe Regents of the University of California
InventorMarc K. Hellerstein
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Abstract
The present invention relates to a labeled deoxyribonucleic acid (DNA) molecule. In one aspect, the labeled DNA molecule is produced by contacting a cell or subject with a detectable amount of a stable isotope label which is incorporated into DNA via the de novo nucleotide synthesis pathway to produce the labeled DNA molecule.
Claims33
An isolated, labeled DNA molecule, wherein said isolated, labeled DNA molecule is produced by contacting a cell with a detectable amount of a stable isotope label which is incorporated into DNA via de novo nucleotide synthesis pathway to produce labeled DNA, and isolating said labeled DNA.
An isolated, labeled DNA molecule, wherein said isolated labeled DNA molecule is produced by administering a detectable amount of a stable isotope label to a subject, which stable, isotope label is incorporated into DNA of the subject via de novo nucleotide synthesis pathway to produce labeled DNA, and isolating said labeled DNA.
Dependencies are inferred from the claim text.